Senior Instrumentation Technician (Various Shifts: Days, Swing, Grave)

Company: Amgen
Location: Thousand Oaks
Posted on: March 31, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Instrumentation Technician What you will do Lets do this. Lets change the world. In this vital role you will be responsible for maintaining and calibrating instrumentation systems and performing advanced troubleshooting and maintenance activities at the Amgen Thousand Oaks site. This role supports a 24/7 GMP biopharmaceutical manufacturing operation, ensuring the reliability and compliance of critical manufacturing and utility systems. This position may support day, swing, or night shifts, including weekends and holidays, to ensure continuous site coverage. Shift differential compensation may apply for eligible off-shift assignments. Perform scheduled calibration, preventive maintenance, and corrective maintenance on instrumentation and control systems used across the site Troubleshoot and repair complex instrumentation systems, and related equipment supporting manufacturing and utilities operations Serve as a subject matter expert for instrumentation systems and provide advanced technical troubleshooting support Ensure activities are performed safely and in compliance with cGMP requirements, regulatory standards, and site procedures Strict adherence to Standard Operating Procedures (SOPs), data integrity practices, and maintenance documentation requirements Provide technical guidance and mentorship to other technicians and peers Coordinate and communicate maintenance activities with system owners, operators, engineers, and key stakeholders Ensure work order documentation and calibration records are completed accurately and thoroughly in the CMMS system Identify equipment reliability risks, workflow interruptions, and opportunities for process improvement; recommend and assist with implementation of solutions Identify opportunities to expand technical capabilities and contribute to overall team development and performance Provide operational support when required, including outside normal working hours, to maintain uninterrupted 24/7 manufacturing operations What we expect of you We are all different, yet we all use our unique contributions to serve patients. The senior technical professional we seek is a self-starter with these qualifications. Basic Qualifications: High school/GED 2 years operations, maintenance, manufacturing work experience or military experience OR Associates 6 months operations, maintenance, manufacturing work experience or military experience Preferred Qualifications: Extensive experience with instrument calibration, troubleshooting, and maintenance of process instrumentation Experience supporting GMP-regulated pharmaceutical or biopharmaceutical manufacturing environments 2 years in a technical school setting with 4 years of hands-on experience in operations or manufacturing Strong understanding of process control systems and instrumentation such as temperature, pressure, flow, level, pH, and analytical instruments Experience supporting GMP utilities systems such as WFI, clean steam, compressed gases, and HVAC Strong troubleshooting and root cause analysis skills for complex instrumentation issues Ability to mentor and provide technical guidance to other technicians Effective written and verbal communication skills Ability to collaborate effectively with cross-functional teams including engineering, operations, and maintenance Computer skills including CMMS and electronic documentation systems Demonstrated commitment to safety, compliance, and continuous improvement What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Amgen, Montebello , Senior Instrumentation Technician (Various Shifts: Days, Swing, Grave), Engineering , Thousand Oaks, California